DENYear-round
Denver (DEN)
Southwest · United · Frontier
12× daily770 mi$125–$250
STLInternational
Nonstop flights from St Louis (STL)
St. Louis Lambert International Airport · St Louis, MO · large airport
STL has 60 nonstop destinations, including Denver, Atlanta and Chicago. Every route below is a direct flight from St Louis, busiest first.
60nonstop routes
Yesscheduled service
38.7487° N, 90.3700° W
Direct flights from St Louis (STL)
60 nonstop destinations — busiest first, with departures per week
Flight counts are departures actually operated in July 2026, and fares are the middle half of one-way tickets sold in the Q2 2025 survey, both from US DOT filings. Routes without a published fare sample show no price.
ATLYear-round
Hartsfield Jackson Atlanta (ATL)
Delta · Southwest · Frontier
11× daily484 mi$125–$300
ORDYear-round
Chicago O'Hare (ORD)
American · United · SkyWest · Republic
9× daily258 mi$150–$325
MCOYear-round
Orlando (MCO)
Southwest · Frontier
7× daily882 mi$100–$275
DFWYear-round
Dallas Fort Worth (DFW)
American · Frontier · SkyWest
7× daily550 mi$150–$325
PHXYear-round
Phoenix Sky Harbor (PHX)
Southwest · American · Frontier
6× daily1,262 mi$175–$325
LGAYear-round
LaGuardia (LGA)
Southwest · Republic
6× daily888 mi$125–$250
LASYear-round
Harry Reid (LAS)
Southwest · Frontier
6× daily1,371 mi$150–$325
DCAYear-round
Ronald Reagan Washington National (DCA)
Southwest · American · Republic
6× daily719 mi$125–$275
DALYear-round
Dallas Love Field (DAL)
Southwest
6× daily546 mi$125–$300
MSPYear-round
Minneapolis–Saint Paul International Airport / Wold–Chamberlain Field (MSP)
Delta · Southwest · SkyWest
6× daily448 mi$150–$300
CLTYear-round
Charlotte Douglas (CLT)
American · Southwest
6× daily575 mi$175–$300
DTWYear-round
Detroit Metropolitan Wayne County (DTW)
Delta · Southwest · SkyWest
6× daily440 mi$125–$325
MDWYear-round
Chicago Midway (MDW)
Southwest
5× daily251 mi$100–$300
HOUYear-round
William P. Hobby (HOU)
Southwest
5× daily687 mi$125–$275
BOSYear-round
Boston Logan (BOS)
Southwest · Republic · American
5× daily1,047 mi$200–$375
PHLYear-round
Philadelphia (PHL)
American · Southwest · Republic
5× daily814 mi$175–$375
SEASummer only
Seattle–Tacoma (SEA)
Alaska · Southwest
4× daily1,709 mi$175–$325
BWIYear-round
Baltimore/Washington International Thurgood Marshall (BWI)
Southwest
4× daily738 mi$150–$300
BNAYear-round
Nashville (BNA)
Southwest
4× daily272 mi$125–$325
TPAYear-round
Tampa (TPA)
Southwest · Frontier
3× daily869 mi$150–$300
MIAYear-round
Miami (MIA)
American · Southwest
3× daily1,068 mi$175–$300
MCIYear-round
Kansas City (MCI)
Southwest
3× daily237 mi$150–$350
SLCYear-round
Salt Lake City (SLC)
Delta · Southwest
3× daily1,156 mi$200–$375
LAXYear-round
Los Angeles (LAX)
Southwest · SkyWest
3× daily1,592 mi$175–$325
AUSYear-round
Austin Bergstrom (AUS)
Southwest
3× daily721 mi$125–$275
EWRYear-round
Newark Liberty (EWR)
Republic · United
daily872 mi$175–$325
FLLYear-round
Fort Lauderdale Hollywood (FLL)
Southwest
daily1,057 mi$125–$275
OMAYear-round
Eppley Airfield (OMA)
Southwest
daily342 mi$175–$325
RSWYear-round
Southwest Florida (RSW)
Southwest
daily979 mi$150–$300
SFOYear-round
San Francisco (SFO)
Southwest · United · SkyWest
daily1,735 mi$200–$350
RDUYear-round
Raleigh-Durham (RDU)
Southwest
daily668 mi$150–$300
CLEYear-round
Cleveland Hopkins (CLE)
Southwest
daily487 mi$125–$275
CMHYear-round
John Glenn Columbus (CMH)
Southwest
daily409 mi$125–$300
MKEYear-round
General Mitchell (MKE)
Southwest
daily317 mi$150–$300
MSYYear-round
Louis Armstrong New Orleans (MSY)
Southwest
daily604 mi$150–$300
PITYear-round
Pittsburgh (PIT)
Southwest
daily554 mi$125–$300
SATYear-round
San Antonio (SAT)
Southwest
daily786 mi$125–$300
ECPSummer only
Northwest Florida Beaches (ECP)
Southwest
daily634 mi$175–$300
JAXYear-round
Jacksonville (JAX)
Southwest
daily753 mi$125–$250
SANYear-round
San Diego (SAN)
Southwest
daily1,557 mi$200–$400
PDXSummer only
Portland (PDX)
Alaska · Southwest
daily1,708 mi$250–$400
PNSSummer only
Pensacola (PNS)
Southwest
daily598 mi$150–$275
SRQYear-round
Sarasota Bradenton (SRQ)
Southwest
daily903 mi$150–$250
VPSSummer only
Destin-Fort Walton Beach (VPS)
Southwest
daily610 mi$150–$275
CHSSummer only
Charleston (CHS)
Southwest
daily706 mi$150–$275
SAVSummer only
Savannah Hilton Head (SAV)
Southwest
daily689 mi$175–$300
SMFYear-round
Sacramento (SMF)
Southwest
daily1,679 mi$250–$400
IAHYear-round
George Bush Intercontinental (IAH)
United · SkyWest
6× weekly667 mi$175–$375
MYRSummer only
Myrtle Beach (MYR)
Southwest
6× weekly728 mi$175–$250
BURYear-round
Hollywood Burbank/Bob Hope (BUR)
Southwest
2× weekly1,583 mi$200–$350
SJUYear-round
Luis Muñoz Marín (SJU)
Southwest
1× weekly2,024 mi$250–$375
CUNYear-round
Cancún
Southwest · Frontier
DSMWinter only
Des Moines (DSM)
Southwest
0× weekly259 mi$100–$300
ICTWinter only
Wichita Dwight D. Eisenhower National (ICT)
Southwest
0× weekly392 mi$100–$325
LHRYear-round
London Heathrow
British Airways
LITWinter only
Bill & Hillary Clinton National Airport/Adams Field (LIT)
Southwest
0× weekly296 mi$75–$275
OKCWinter only
OKC Will Rogers World (OKC)
Southwest
0× weekly462 mi$150–$325
TULWinter only
Tulsa (TUL)
Southwest
0× weekly351 mi$75–$325
YYZYear-round
Toronto Pearson
Air Canada
Other airports near St Louis
Closest MO airports with scheduled service
COU
Columbia
Columbia Regional Airport
MOScheduled6 routes
CGI
Cape Girardeau
Cape Girardeau Regional Airport
MOScheduled
No nonstop routes published yet
TBN
Fort Leonard Wood
Waynesville-St. Robert Regional Airport-Forney Field
MOScheduled
No nonstop routes published yet
IRK
Kirksville
Kirksville Regional Airport
MOScheduled
No nonstop routes published yet
SGF
Springfield
Springfield Branson National Airport
MOScheduled13 routes
BKG
Branson
Branson Airport
MOScheduled
No nonstop routes published yet