Nonstop route
St Louis to Des Moines nonstop
Yes — Southwest flies STL to DSM nonstop in the winter season only — about 0× weekly.
STLSt Louis
✈
DSMDes Moines
0× weekly0 flights a week
Winter only0/wk Jun vs 13.1/wk Jan
$100–$300typical one-way · median $175
259miles nonstop
Affiliate disclosure
Ready to compare fares?
Fares are what people actually paid: half of the 263 tickets in the US DOT fare survey for this route sold between $100 and $300 one way, median $175. That survey runs a couple of quarters behind, so treat it as the shape of the route's pricing rather than today's quote.
Nonstop Scout may earn revenue from outbound flight-search links.