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Nonstop route

St Louis to Tampa nonstop

Yes — Southwest and Frontier fly STL to TPA nonstop year-round — about 3× daily.

STLSt Louis
TPATampa

Southwest · Frontier

3× daily23.1 flights a week
Year-round23.1/wk Jun vs 22.8/wk Jan
$150–$300typical one-way · median $200
869miles nonstop
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Fares are what people actually paid: half of the 1,982 tickets in the US DOT fare survey for this route sold between $150 and $300 one way, median $200. That survey runs a couple of quarters behind, so treat it as the shape of the route's pricing rather than today's quote.

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