Nonstop route
Chicago to St. Louis nonstop
Yes — Southwest flies MDW to STL nonstop year-round — about 5× daily.
MDWChicago
✈
STLSt. Louis
5× daily37.1 flights a week
Year-round37.1/wk Jun vs 27.1/wk Jan
$100–$300typical one-way · median $175
251miles nonstop
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Fares are what people actually paid: half of the 1,645 tickets in the US DOT fare survey for this route sold between $100 and $300 one way, median $175. That survey runs a couple of quarters behind, so treat it as the shape of the route's pricing rather than today's quote.
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