Nonstop route
Detroit to Boston nonstop
Yes — Delta and JetBlue fly DTW to BOS nonstop year-round — about 7× daily.
DTWDetroit
✈
BOSBoston
7× daily50.4 flights a week
Year-round50.4/wk Jun vs 34.5/wk Jan
$100–$300typical one-way · median $175
632miles nonstop
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Fares are what people actually paid: half of the 6,018 tickets in the US DOT fare survey for this route sold between $100 and $300 one way, median $175. That survey runs a couple of quarters behind, so treat it as the shape of the route's pricing rather than today's quote.
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