Nonstop route
Columbus to St. Louis nonstop
Yes — Southwest flies CMH to STL nonstop year-round — about daily.
CMHColumbus
✈
STLSt. Louis
daily13.1 flights a week
Year-round13.1/wk Jun vs 12.2/wk Jan
$125–$300typical one-way · median $200
409miles nonstop
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Fares are what people actually paid: half of the 634 tickets in the US DOT fare survey for this route sold between $125 and $300 one way, median $200. That survey runs a couple of quarters behind, so treat it as the shape of the route's pricing rather than today's quote.
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