Nonstop route
San Diego to Fresno nonstop
Yes — Southwest flies SAN to FAT nonstop year-round — about 5× daily.
SANSan Diego
✈
FATFresno
5× daily33.8 flights a week
Year-round33.8/wk Jun vs 30.7/wk Jan
$100–$225typical one-way · median $150
314miles nonstop
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Fares are what people actually paid: half of the 1,558 tickets in the US DOT fare survey for this route sold between $100 and $225 one way, median $150. That survey runs a couple of quarters behind, so treat it as the shape of the route's pricing rather than today's quote.
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