Nonstop route
Raleigh/Durham to Chicago nonstop
Yes — Southwest flies RDU to MDW nonstop year-round — about 3× daily.
RDURaleigh/Durham
✈
MDWChicago
3× daily20.5 flights a week
Year-round20.5/wk Jun vs 13.8/wk Jan
$100–$225typical one-way · median $150
632miles nonstop
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Fares are what people actually paid: half of the 1,619 tickets in the US DOT fare survey for this route sold between $100 and $225 one way, median $150. That survey runs a couple of quarters behind, so treat it as the shape of the route's pricing rather than today's quote.
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