Nonstop route
Chicago to Jacksonville nonstop
Yes — United and American fly ORD to JAX nonstop year-round — about 7× daily.
ORDChicago
✈
JAXJacksonville
7× daily46 flights a week
Year-round46/wk Jun vs 35.9/wk Jan
$175–$350typical one-way · median $225
864miles nonstop
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Fares are what people actually paid: half of the 2,189 tickets in the US DOT fare survey for this route sold between $175 and $350 one way, median $225. That survey runs a couple of quarters behind, so treat it as the shape of the route's pricing rather than today's quote.
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