Nonstop route
Chicago to Panama City nonstop
Yes — Republic, SkyWest and Envoy fly ORD to ECP nonstop in the summer season only — about daily.
ORDChicago
✈
ECPPanama City
daily14.5 flights a week
Summer only14.5/wk Jun vs 1.1/wk Jan
$150–$300typical one-way · median $200
810miles nonstop
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Fares are what people actually paid: half of the 519 tickets in the US DOT fare survey for this route sold between $150 and $300 one way, median $200. That survey runs a couple of quarters behind, so treat it as the shape of the route's pricing rather than today's quote.
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