Nonstop route
Minneapolis to Pittsburgh nonstop
Yes — Delta flies MSP to PIT nonstop in the summer season only — about 3× daily.
MSPMinneapolis
✈
PITPittsburgh
3× daily21 flights a week
Summer only21/wk Jun vs 2.3/wk Jan
$200–$400typical one-way · median $275
726miles nonstop
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Fares are what people actually paid: half of the 1,004 tickets in the US DOT fare survey for this route sold between $200 and $400 one way, median $275. That survey runs a couple of quarters behind, so treat it as the shape of the route's pricing rather than today's quote.
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