Nonstop route
Chicago to Buffalo nonstop
Yes — Southwest flies MDW to BUF nonstop in the summer season only — about 3× daily.
MDWChicago
✈
BUFBuffalo
3× daily20.5 flights a week
Summer only20.5/wk Jun vs 6.5/wk Jan
$125–$250typical one-way · median $150
468miles nonstop
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Fares are what people actually paid: half of the 448 tickets in the US DOT fare survey for this route sold between $125 and $250 one way, median $150. That survey runs a couple of quarters behind, so treat it as the shape of the route's pricing rather than today's quote.
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