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Nonstop route

Key West to Charlotte nonstop

Yes — American flies EYW to CLT nonstop year-round — about 3× daily.

EYWKey West
CLTCharlotte

American · operated in part by Envoy

3× daily20.1 flights a week
Year-round20.1/wk Jun vs 24.8/wk Jan
$275–$425typical one-way · median $300
736miles nonstop
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Fares are what people actually paid: half of the 319 tickets in the US DOT fare survey for this route sold between $275 and $425 one way, median $300. That survey runs a couple of quarters behind, so treat it as the shape of the route's pricing rather than today's quote.

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