Nonstop route
Charlotte to Columbus nonstop
Yes — American flies CLT to CMH nonstop year-round — about 6× daily.
CLTCharlotte
✈
CMHColumbus
6× daily39.2 flights a week
Year-round39.2/wk Jun vs 31.8/wk Jan
$225–$450typical one-way · median $350
347miles nonstop
Affiliate disclosure
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Fares are what people actually paid: half of the 826 tickets in the US DOT fare survey for this route sold between $225 and $450 one way, median $350. That survey runs a couple of quarters behind, so treat it as the shape of the route's pricing rather than today's quote.
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