Nonstop route
Charlotte to Buffalo nonstop
Yes — American flies CLT to BUF nonstop year-round — about 3× daily.
CLTCharlotte
✈
BUFBuffalo
3× daily20.8 flights a week
Year-round20.8/wk Jun vs 18.5/wk Jan
$125–$275typical one-way · median $175
546miles nonstop
Affiliate disclosure
Ready to compare fares?
Fares are what people actually paid: half of the 1,273 tickets in the US DOT fare survey for this route sold between $125 and $275 one way, median $175. That survey runs a couple of quarters behind, so treat it as the shape of the route's pricing rather than today's quote.
Nonstop Scout may earn revenue from outbound flight-search links.