Nonstop route
Columbus to Myrtle Beach nonstop
Yes — Southwest flies CMH to MYR nonstop in the summer season only — about 2× weekly.
CMHColumbus
✈
MYRMyrtle Beach
2× weekly1.9 flights a week
Summer only1.9/wk Jun vs 0/wk Jan
$100–$200typical one-way · median $150
488miles nonstop
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Fares are what people actually paid: half of the 96 tickets in the US DOT fare survey for this route sold between $100 and $200 one way, median $150. That survey runs a couple of quarters behind, so treat it as the shape of the route's pricing rather than today's quote.
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